Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  2
• Reference
  J:17867 Miller MW, et al., The mouse lethal nonagouti (a(x)) mutation deletes the S-adenosylhomocysteine hydrolase (Ahcy) gene. EMBO J. 1994 Apr 15;13(8):1806-16
• ID
  MGI:43404

Genes

Gene	Assay Type	Description
a	Southern analysis	probe c, probe e
Ahcy	Southern analysis	pDEC20-1

Notes

• Experiment
  Using Southern analysis with a contig built around the agouti locus, the authors were able to state the Ahcy gene (contained on a 20kb region) lay 6kb distal to the 3'end of the agouti coding region. The a^x mutation is a 100kb deletion which completelyremoves the Ahcy gene that codes for the S-adenosylhomocysteine hydrolase enzyme.