Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  3
• Reference
  J:18530 Kingsmore SF, et al., Glycine receptor beta-subunit gene mutation in spastic mouse associated with LINE-1 element insertion. Nat Genet. 1994 Jun;7(2):136-41
• ID
  MGI:43509

Genes

Gene	Assay Type	Description
Gria2	reported elsewhere
Glrb	Southern analysis	pCRII-rgerb1
Gba1	reported elsewhere

Notes

• Reference
  The authors suggest that Glrb is a candidate gene for the spa phenotype.
• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <c> <c> <c>/<s> <s> <s>
• Strain
  (C3H/HeJ-Fasl x M. spretus)F1
• Male Parent
  <c> <c> <c>/<c> <c> <c>
• Strain
  C3H/HeJ-Fasl/J
• Mapping Panel
  Seldin
• Allele 1
  c from C3H/HeJ-Fasl/J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Gria2	Glrb	Gba1
52	c	c	c
55	s	s	s
1	c	s	s
1	s	c	c
3	c	c	s
2	s	s	c

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Gria2	Glrb	2	114	1.754	1.230
Glrb	Gba1	5	114	4.386	1.918