Mapping Data

Experiment

• Experiment
  TEXT-Physical Mapping
• Chromosome
  17
• Reference
  J:17944 Hanson IM, et al., Colinearity of novel genes in the class II regions of the MHC in mouse and human. Immunogenetics. 1991;34(1):5-11
• ID
  MGI:43563

Genes

Gene	Assay Type
Rps18	overlapping clones
H2-K2	reported elsewhere
H2-K1	reported elsewhere
D17H6S111E	overlapping clones
Hsd17b8	overlapping clones
Slc39a7	overlapping clones
H2-Pb	reported elsewhere
Brd2	overlapping clones
Tap1	overlapping clones
H2-Ob	reported elsewhere

Notes

• Experiment
  Detailed physical mapping of overlapping cosmids and cross-hybridization to human cDNAs placed D176H11E, D17H6S112E and H2-Ke4 55kb, 50kb and 45kb proximal to H2-Pb, respectively (data not shown). Using the same techniques, D17H6S113E was shown to be approximately 30-40kb distal of H2-Pb and Abcb2 was 40kb proximal of H2-Ob. Authors state the order of genes in mice is: Rps18 - H2-K2 - H2-K - D17H6S111E - D17H6S112E. This provides an order in the MHC class II region which is conserved in both the human and the mouse.