Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  X
• Reference
  J:19674 Stambolian D, et al., Mapping of the X-linked cataract (Xcat) mutation, the gene implicated in the Nance Horan syndrome, on the mouse X chromosome. Genomics. 1994 Jul 15;22(2):377-80
• ID
  MGI:43717

Genes

Gene	Assay Type	Description
DXMit28	PCR amplified length variant	B491
DXWas31	Southern analysis	DXWas31 probe1
DXPas18	Southern analysis	DXPas18 probe1
DXMit20	PCR amplified length variant	D542
Nhs	visible phenotype
DXMit15	PCR amplified length variant	B248
Grpr	PCR amplified length variant	Grpr-pA, Grpr-pB
Amelx	Southern analysis	pMA5-5
DXMit12	PCR amplified length variant	B336

Notes

• Experiment
  32 males and 26 females were tested in this cross. Female homozygous mice carrying the Xcat mutation on a partial congenic DBA/2 background were mated to normal M. spretus males.

CROSS

• Type
  Backcross, female
• Female Parent
  <d> <d> <d> <d> <d> <d> <d> <d> <d>/<s> <s> <s> <s> <s> <s> <s> <s> <s>
• Strain
  (DBA/2 x M. spretus)F1
• Male Parent
  <d> <d> <d> <d> <d> <d> <d> <d> <d>/Y
• Strain
  C57BL/6J
• Allele 1
  d from DBA/2 and C57BL/6J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	DXMit28	DXWas31	DXPas18	DXMit20	Nhs	DXMit15	Grpr	Amelx	DXMit12
26	s	s	s	s	s	s	s	s	s
27	d	d	d	d	d	d	d	d	d
1	s	d	d	d	d	d	d	d	d
2	d	s	s	s	s	s	s	s	s
2	s	s	s	s	s	s	s	d	d

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
DXMit28	DXWas31	3	58	5.172	2.908
DXWas31	DXPas18	0	58	0.000	0.000
DXPas18	DXMit20	0	58	0.000	0.000
DXMit20	Nhs	0	58	0.000	0.000
Nhs	DXMit15	0	58	0.000	0.000
DXMit15	Grpr	0	58	0.000	0.000
Grpr	Amelx	2	58	3.448	2.396
Amelx	DXMit12	0	58	0.000	0.000