Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  4
• Reference
  J:18590 Raymond S, et al., Molecular characterization of the mouse B^w mutation causing premature melanocyte death - melanocytes and early development. Genet Res. 1994;63(2):155 (Abstr)
• ID
  MGI:43993

Genes

Gene	Allele	Assay Type	Description
Tyrp1	Tyrp1^b	Southern analysis	b genomic1

Notes

• Reference
  b is an allele of Tyrp1.
• Experiment
  While investigating the cause of the B^w phenotype the authors found that an inversion in Tyrp may bring enhancer elements into cross proximity to a downstream toxic gene. Expression of this leads to death of melanocytes, and consequently, the B^w phenotype.