Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  2
• Reference
  J:153399 Everett ET, et al., Detection of dental fluorosis-associated quantitative trait Loci on mouse chromosomes 2 and 11. Cells Tissues Organs. 2009;189(1-4):212-8
• ID
  MGI:4418088

Genes

Gene	Description
Dfs1	rs13476589 and UT_2_156.443943

Notes

• Experiment
  A/J mice are susceptible to dental fluorosis whereas 129/F3 mice are resistant. A total of 458 (A/J X 129P3)F2 mice were analyzed in a genome wide scan(354 SNPs) to map QTL that effect susceptibility to fluorosis in mice. A significant association was found in mouse Chromosome 2 and 11. The chromosome 2 QTL , Dfs1, segregated with flanking markers rs13476589 and UT_2_156.443943. The QTL interval in chromosome 11 for Dfs2 was defined by flanking markers rs3708339 and rs6161623. A suggested genome location for Dfs1 was 77.62 Mb and 74.29 for Dfs2.