Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  17
• Reference
  J:9387 Aldrich CJ, et al., Regulation of Qa-1 expression and determinant modification by an H-2D-linked gene, Qdm. Immunogenetics. 1988;28(5):334-44
• ID
  MGI:44761

Genes

Gene	Assay Type
Qdm	immunological
H2-S	immunological
Qa2	immunological
Neu1	reported elsewhere
C4a	reported elsewhere

Notes

• Experiment
  Qdm modifies Qa1 (now H2-Q1). Using a series of H2 congenic mice, Qdm was found to map to the left of Qa2 (now H2-Q7, H2-Q8, H2-Q9). and thus is also not allelic with H2-Q1. Further, Qdm was found to map to the right of Slp (now C4a), thus placing it in the H2-D region of Chromosome 17. Neu1 (18.93 cM) is a potential candidate gene mapping to the Qdm interval.
  
  C57BL/6J animals carry the dominant Qdm⁺ allele while CBA/J, C3H, and AKR carry the recessive Qdm^k allele.