Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  1
• Reference
  J:20323 Copp AJ, et al., Developmental basis of severe neural tube defects in the loop-tail (Lp) mutant mouse: use of microsatellite DNA markers to identify embryonic genotype. Dev Biol. 1994 Sep;165(1):20-9
• ID
  MGI:44791

Genes

Gene	Allele	Assay Type
Vangl2	Vangl2^Lp	visible phenotype
Crp		other

Notes

• Experiment
  The authors report that in a recent mapping study (Stanier, Eddleston, Henson, Moore and Copp, unpublished) there were no recombinants between Vangl2 and Crp in 245 backcross progeny. This implies that Ltap and Crp lie within 1.2 cM of each other on Chromosome 1. In addition the authors indicated that Vangl2 and Crp have been coupling since the origin of inbred LPT/Le suggesting an absence of crossing over between these loci for 100 generations of inbreeding.