Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  11
• Reference
  J:22810 Juriloff DM, et al., The major locus for multifactorial nonsyndromic cleft lip maps to mouse chromosome 11. Mamm Genome. 1995 Feb;6(2):63-9
• ID
  MGI:44987

Genes

Gene	Assay Type	Description
D11Mit67	PCR amplified length variant	B654
D11Mit132	PCR amplified length variant	MMH359
D11Mit123	PCR amplified length variant	D1056
D11Mit59	PCR amplified length variant	D620
D11Mit124	PCR amplified length variant	MPC916
D11Mit58	PCR amplified length variant	D563
Wnt9b	visible phenotype
D11Mit10	PCR amplified length variant	M162
D11Mit126	PCR amplified length variant	MPC958
D11Mit166	PCR amplified length variant	MPC1300
D11Mit147	PCR amplified length variant	MT22

Notes

• Experiment
  A congenic strain, AEJ.A, was constructed by transferring the cleft lip (clf1) trait from strain A/WySn to a genetically normal strain, AEJ/RkBc. It was determined that D11Mit10 cotransferred with clf1 in several of the AEJ.A carrier males. Through analysis of neighboring Chromosome 11 SSLPs the authors were able to define the clf1-containing region was between D11Mit67 and D11Mit147. They also determined that the order of loci in this region is: D11Mit67, D11Mit132, D11Mit123, D11Mit59, D11Mit124, D11Mit58, clf1, D11Mit10, D11Mit126, D11Mit166, D11Mit147. The genotypes of 16 AEJ.A proven clf1 carrier males is provided in the reference.