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Mapping Data
Experiment
  • Experiment
    TEXT-Genetic Cross
  • Chromosome
    4
  • Reference
    J:24933 Nolan PM, et al., Heterozygosity mapping of partially congenic lines: mapping of a semidominant neurological mutation, Wheels (Whl), on mouse chromosome 4. Genetics. 1995 May;140(1):245-54
  • ID
    MGI:45137
Genes
GeneAlleleAssay TypeDescription
D4Mit149 PCR amplified length variant
D4Mit181 PCR amplified length variant
Whl visible phenotype
D4Mit1 PCR amplified length variant
D4Mit105 PCR amplified length variant
D4Mit97 PCR amplified length variant
Notes
  • Experiment
    Wheels (symbol Whl) is a ENU induced semidominant behavioral mutant on a BALB/c background. A locus for Whl was mapped to mouse Chromosome 4 by taking advantage of a partially congenic line derived by outcrossing the heterozygous founder mouse to C57BL/6J for 2 generations. The 13 affected G3 mice were then tested for heterozygosity of BALB/c and C57BL/6J alleles at 68 PCR based markers. A significant association of the mutant phenotype with Chromosome 4 subcentromeric markers D4Mt149, D4Mit181, D4Mit1, D4Mit105 and D4Mit97 was indicated.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory