Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  6
• Reference
  J:23328 Dallas-Pedretti A, et al., A diabetes-associated T-cell autoantigen maps to a telomeric locus on mouse chromosome 6. Proc Natl Acad Sci U S A. 1995 Feb 28;92(5):1386-90
• ID
  MGI:45350

Genes

Gene	Assay Type	Description
D6Mit25	PCR amplified length variant	A1121
D6Mit58	PCR amplified length variant
D6Mit60	PCR amplified length variant	MPC675
Ht6.9	immunological	BDC-6.9 antigen
D6Mit57	PCR amplified length variant	MPC670

Notes

• Experiment
  One hundred five backcross mice derived from BALB/cByJ female mice mated to (BALB/cByJ x NOD/Bdc)F1 mice were used to map the gene encoding antigen specificity of T-cell clone BDC-6.9. Complete correlation was observed of the inheritance of the antigen phenotype with Chromosome 6 microsatellites D6Mit58 and D6Mit60. Thus, the gene (Ht6.9) associated with the expression of BDC-6.9 is within the telomeric region of Chromosome 6 bounded proximally by D6Mit25 and distally by D6Mit57.