Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  18
• Reference
  J:27407 Pathak BG, et al., Mouse chromosomal location of three EGF receptor ligands: amphiregulin (Areg), betacellulin (Btc), and heparin-binding EGF (Hegfl). Genomics. 1995 Jul 1;28(1):116-8
• ID
  MGI:45701

Genes

Gene	Assay Type	Description
Ttr	reported elsewhere
Apc	reported elsewhere
Hbegf	Southern analysis	Hegfl cDNA1
Fgf1	reported elsewhere

Notes

• Reference
  Because the sequence and RFLV sizes are nearly identical and because Sdgf and Areg cosegregated in 183 mice, the authors suggest that Sdgf and Areg are species variants derived from the same gene.
• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b>/<s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b>/<b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  Copeland-Jenkins
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Ttr	Apc	Hbegf	Fgf1
72	b	b	b	b
49	s	s	s	s
5	s	b	b	b
5	b	s	s	s
0	s	s	b	b
0	b	b	s	s
4	s	s	s	b
3	b	b	b	s

Additional Mice Typed Only for Specific Pairs of Loci

Marker 1	Marker 2	# Recombinants	# Parentals
Ttr	Apc	4	22
Apc	Hbegf	0	26
Hbegf	Fgf1	1	23

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Ttr	Apc	14	164	8.537	2.182
Apc	Hbegf	0	164	0.000	0.000
Hbegf	Fgf1	8	162	4.938	1.702