Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  17
• Reference
  J:29545 Pham-Dinh D, et al., Physical mapping of the human and mouse MOG gene at the distal end of the MHC class Ib region. Immunogenetics. 1995;42(5):386-91
• ID
  MGI:45769

Genes

Gene	Assay Type	Description
H2-M6-ps	overlapping clones	E12, cosmid 14A
H2-M4-ps	overlapping clones	E12, cosmid 14A, cosmid 2C
H2-M5	overlapping clones	E12, cosmid 2C
Mog	overlapping clones	E12, E7, G11, N1

Notes

• Reference
  Authors use Tu32A for locus symbol D17Tu32A.
• Experiment
  Mog was physcially mapped distal to H2-M5 on mouse Chromosome 17 when YAC clones were screened by Southern analysis with a Mog cDNA probe. Four positive YACS, N1, G11, E7 and E12 were detected, all of which shared the genes H2-M6, H2-M4 and H2-M5. Additionally cosmid 14A and cosmid 2C, which share H2-M6, H2-M4 and H2-M5, tested negative for the presence of Mog by Southern analysis with the Mog specific probes Ex2 and Ex6-7 indicating that Mog maps distal to H2-M5. These data map Mog to mouse Chromosome 17 in the following gene order: H2-M6, H2-M4, H2-M5, Mog. Restriction analysis of YAC E12 further refined the location of Mog to a position 25kb telomeric to H2-M5.