Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  2
• Reference
  J:28726 Dreger RT, et al., The first arch (Far) mutation in mice recombines with Hoxd and Mdk. Mamm Genome. 1995 Sep;6(9):662-3
• ID
  MGI:45773

Genes

Gene	Assay Type	Description
D2Mit11	PCR amplified length variant	M134
Far	visible phenotype
D2Mit75	PCR amplified length variant	B699
Mdk	PCR amplified length variant	D2Tfv1, D2Tfv2

Notes

• Experiment
  The Far mutation arose on a BALB/CGA mouse. In order to map Far relative to Chromosome 2 markers, the authors typed two Far/Far fetuses obtained from an (ICR.BALB-Far x AEJ/RkBc)F1 intercross for Mdk and D2Mit11. Both fetuses were homozygous for the BALBallele of D2Mit11. This indicates that while D2Mit11 is within the chromosomal segment containing Far, Mdk is not. Other studies (Peichel and Vogt, unpublished data) have localized Mdk 1.8 cM distal to D2Mit75 providing further evidence that Far is not a mutation at the Mdk locus.