Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  9
• Reference
  J:29464 Prochazka M, et al., Genetic control of diabetogenesis in NOD/Lt mice. Development and analysis of congenic stocks. Diabetes. 1989 Nov;38(11):1446-55
• ID
  MGI:45842

Genes

Gene	Assay Type	Description
Ldlr	Southern analysis	pHH1
Ets1	Southern analysis	pRD700
Thy1	Southern analysis	pcD-29-5A
Apoa1	immunological
Cyp1a2	Southern analysis	P3450FL
Me1	Southern analysis	Mod1 cDNA

Notes

• Reference
  Authors use P450-3 for locus symbol Cyp1a2. Authors provide evidence that demonstrates that Idd2 is not the product of Thy1.

CROSS

• Type
  Backcross, sexes unspecified or combined
• Female Parent
  <d> <d> <d> <d> <d> <d>/<n> <n> <n> <n> <n> <n>
• Strain
  (NOD/Lt x NON/Lt)F1
• Male Parent
  <d> <d> <d> <d> <d> <d>/<d> <d> <d> <d> <d> <d>
• Strain
  NOD/ShiLt
• Allele 1
  d from NOD/ShiLt
• Allele 2
  n from NON/ShiLt

CROSS Data

MC #mice	Ldlr	Ets1	Thy1	Apoa1	Cyp1a2	Me1
8	d	d	d	d	d	d
1	n	n	n	n	n	n
2	n	n	n	n	n	d
2	d	d	d	d	d	n
3	d	d	d	d	n	n
2	n	n	d	d	d	d
1	n	d	d	d	d	d

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Ldlr	Ets1	1	19	5.263	5.123
Ets1	Thy1	2	19	10.526	7.041
Thy1	Apoa1	0	19	0.000	0.000
Apoa1	Cyp1a2	3	19	15.789	8.365
Cyp1a2	Me1	4	19	21.053	9.353