Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  6
• Reference
  J:28829 Street VA, et al., Molecular genetic analysis of distal mouse chromosome 6 defines gene order and positions of the deafwaddler and opisthotonos mutations. Genomics. 1995 Sep 1;29(1):123-30
• ID
  MGI:45918

Genes

Gene	Assay Type	Description
Atp2b2	visible phenotype
D6Mit44	PCR amplified length variant
D6Mit12	PCR amplified length variant
Kcna1	Southern analysis	Kcna1 probe1
Kcna5	Southern analysis	Kcna5 probe1

Notes

• Experiment
  In a (CAST/Ei +/+ x C3HeB/FeJ-dfw/dfw or dfw/+)F1 x C3HeB/FeJ backcross, various recombinant mice were analyzed for Kcna1 and Kcna5. Both Kcna1 and Kcna5 mapped distal to D6Mit44 and had segregation patterns similar to D6Mit12. Additional mice need to betested to confirm that D6Mit12, Kcna5 and Kcna1 co-localize on mouse Chromosome 6. These data provide evidence that neither Kcna1 or Kcna5 are candidates for the dfw phenotype.