Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  11
• Reference
  J:24090 Stein D, et al., The SH2 domain protein GRB-7 is co-amplified, overexpressed and in a tight complex with HER2 in breast cancer. EMBO J. 1994 Mar 15;13(6):1331-40
• ID
  MGI:45965

Genes

Gene	Assay Type	Description
Ngfr	Southern analysis	p56
Grb7	Southern analysis	Grb7 probe1
Erbb2	Southern analysis	neuc(t)/sp6300
Csf3	Southern analysis	pBRG-4
D11Mit10	PCR amplified length variant

Notes

• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <a> <a> <a> <a> <a>/<s> <s> <s> <s> <s>
• Strain
  (AEJ/Gn x M. spretus)F1
• Male Parent
  <a> <a> <a> <a> <a>/<a> <a> <a> <a> <a>
• Strain
  AEJ/Gn
• Allele 1
  a from AEJ/Gn
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Ngfr	Grb7	Erbb2	Csf3	D11Mit10
89	a	a	a	a	a
91	s	s	s	s	s
2	s	a	a	a	a
3	a	s	s	s	s
5	s	s	s	s	a
1	a	a	a	a	s

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Ngfr	Grb7	5	191	2.618	1.155
Grb7	Erbb2	0	191	0.000	0.000
Erbb2	Csf3	0	191	0.000	0.000
Csf3	D11Mit10	6	191	3.141	1.262