Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  4
• Reference
  J:30407 Tartaglia LA, et al., Identification and expression cloning of a leptin receptor, OB-R. Cell. 1995 Dec 29;83(7):1263-71
• ID
  MGI:46007

Genes

Gene	Allele	Assay Type	Description
D4Mit9		PCR amplified length variant
D4Mit255		PCR amplified length variant
Lepr	Lepr^db	PCR amplified length variant	Lepr-pA, Lepr-pB
D4Mit155		PCR amplified length variant
D4Mit31		PCR amplified length variant
D4Mit46		PCR amplified length variant

Notes

• Experiment
  Analysis of 183 backcross progeny of the cross (C57BL/6J x SPRET/Ei)F1 females x C57BL/6J males by PCR and SCCP was used to determine the following order of loci on mouse Chromosome 4: D4Mit9 - 1.6 cM - D4Mit255 - 0.6 cM - Lepr - 0.6 cM - D4Mit155 - 3.9 cM - D4Mit31 - D4Mit46. Authors further state that Lepr maps within the 5.1 cM interval between markers D4Mit255 and D4Mit31 on the mouse chromosome 4 that includes the region coding for the diabetic phenotype.