Mapping Data

Experiment

• Experiment
  TEXT-Cytogenetic Localization
• Chromosome
  X
• Reference
  J:27405 De Backer O, et al., Structure, chromosomal location, and expression pattern of three mouse genes homologous to the human MAGE genes. Genomics. 1995 Jul 1;28(1):74-83
• ID
  MGI:46123

Genes

Gene	Assay Type	Description
Mageb1	Southern analysis	Mage-rs1 genomic
Mageb2	Southern analysis	Mage-rs1 genomic

Notes

• Reference
  Authors use DXHX52 and Bmp2-ps1 for locus symbols DXHXS52 and Bmp2-rs1 respectively.
• Experiment
  Mageb1 and Mageb2 were initially mapped to within the proximal half of mouse Chromosome X using mouse x human and mouse x hamster somatic cell hybrids. Authors use analysis of the somatic cell hybrid B20c12, carrying a deleted X mouse chromosome, to separate Mageb1 and Mageb2 They place Mageb1 in a 3 cM region between the breakpoint present in B20c12 and the Ar locus on the mouse X Chromosome and Mageb2 between Dmd and the B20c12 breakpoint, a 2 cM distance. Additionally, authors used the fact that none of the 8 cosmid clones they isolated contained both genes, places Mageb1 and Mageb2 more than 20kb apart on mouse Chromosome X.