Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  11
• Reference
  J:31335 Greco TL, et al., Analysis of the vestigial tail mutation demonstrates that Wnt-3a gene dosage regulates mouse axial development. Genes Dev. 1996 Feb 1;10(3):313-24
• ID
  MGI:46160

Genes

Gene	Allele	Assay Type	Description
D11Mit1		PCR amplified length variant
Egfr	Egfr^wa2	visible phenotype
D11Mit22		PCR amplified length variant
Csf2		PCR amplified length variant
Sparc		Southern analysis	pC33
Wnt3a		visible phenotype
D11Mit5		PCR amplified length variant

Notes

• Reference
  Authors suggest Wnt3a may be responsible for the vt mutation.
• Experiment
  Progeny from a (VT vt/vt x CASA/Rk)F1 x VT vt/vt backcross were typed for makers on the proximal half of mouse Chromosome 11. The following gene order and genetic distances were obtained: D11Mit1 - 14.9 +/- 4.4 cM - Egfr - 18.6 +/- 2.3 cM - D11Mit22 3.6 +/- 1.0 cM - Csfgm - 1.2 +/- 0.8 cM - Sparc - 2.3 +/- 1.1 cM - vt, Wnt3a - 2.2 +/- 0.7 cM - D11Mit5.