Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  11
• Reference
  J:28409 Segre JA, et al., Positional cloning of the nude locus: genetic, physical, and transcription maps of the region and mutations in the mouse and rat. Genomics. 1995 Aug 10;28(3):549-59
• ID
  MGI:46234

Genes

Gene	Allele	Assay Type	Description
D11Seg4		PCR amplified length variant	D11Seg-pA, D11Seg-pB
D11Seg8		PCR amplified length variant	D11Seg8-pA, D11Seg8-pB
Foxn1	Foxn1^nu-str	visible phenotype
D11Seg30		PCR amplified length variant	D11Seg30-pA, D11Seg30-pB
D11Seg41		PCR amplified length variant	D11Seg41-pA, D11Seg41-pB

Notes

• Reference
  The authors use RDA6.2, RDA10.4, RDA10.2, rah GTP, and Ad-Rab for locus symbols D11Seg45, D11Seg46, D11Seg47, Rah1, and D11Seg50 respectively.
• Experiment
  To identify the physical boundries of Hfh11^nu, the authors genetically mapped many ends of the P1 clones by SSCP on progeny of crosses (AKR-Hfh11^nu-str/^nu-str x C57BL/6J)F2, (AKR-Hfh11^nu-str/^nu-str x MOLF/Ei)F2, (AKR-Hfh11^nu-str/^nu-str x CAST/Ei)F2 with the closest flanking crossovers. Based upon the analysis of these progeny, authors determined that the smallest physical region in which the nude was determined to lie is a minimum of 230kb (from D11Seg8 to D11Seg30) and a maximum of 370kb (from D11Seg4 to D11Seg41).