Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  11
• Reference
  J:33172 Yui MA, et al., Production of congenic mouse strains carrying NOD-derived diabetogenic genetic intervals: an approach for the genetic dissection of complex traits. Mamm Genome. 1996 May;7(5):331-4
• ID
  MGI:46669

Genes

Gene	Assay Type
Idd4	resistance/susceptibility
Csf2	reported elsewhere
D11Nds1	reported elsewhere
D11Mit42	PCR amplified length variant

Notes

• Experiment
  Microsatellite sequences were used as co-dominant markers to identify/map NOD mouse intervals containing recessive susceptibility alleles of insulin-related diabetes-associated genes. These intervals were transferred to C57BL/6, a resistant strain background, to produce 6 congenic strains. A gain of phenotype strategy was used in their construction. B6.NODc11 includes the Idd4 interval, mapped to Csfgm - D11Nds1 - D11Mit42 (over 42 cM on mouse Chromosome 11).