Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  5
• Reference
  J:9505 Geissler EN, et al., Genetic analysis of the dominant white-spotting (W) region on mouse chromosome 5: identification of cloned DNA markers near W. Proc Natl Acad Sci U S A. 1988 Dec;85(24):9635-9
• ID
  MGI:46696

Genes

Gene	Allele	Assay Type	Description
D5Mnl25e		Southern analysis	pSC25
Kit	Kit^W-19H	visible phenotype

Notes

• Reference
  Authors use W^19H, D4S76 and D5Sc25 for Kit^W-19H, D5H4S76, and D5Mnl25.
• Experiment
  Authors tested several W-region congenic mouse lines for the occurrence of recombination between D5Mnl25 and Kit^W-19H during transfer of the selected W mutation into a C57BL/6J or C3H/HeJ background. Congenic lines B6.C3H-Kit^W-44 and B6.C3H-Kit^W-39, both of which have gone through 40 to 50 generations of backcrossing, retain the donor alleles at the D5Mnl25 locus, indicating that D5Mnl25 maps within 1 cM of the Kit^W locus. This assertion was further validated by the finding that the B6.C3H-rs line, produced by 30 generations of backcrossing , also retains the donor alleles at the D5Mnl25 locus.