Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  12
• Reference
  J:30855 Mainville CA, et al., Deletional mapping of fifteen mouse VH gene families reveals a common organization for three Igh haplotypes. J Immunol. 1996 Feb 1;156(3):1038-46
• ID
  MGI:46751

Genes

Gene	Assay Type	Description
Igh-VJ558	Southern analysis	VJ558 probe
Igh-V3609	Southern analysis	V3609 genomic
Igh-V15	Southern analysis	V15A
Igh-V10	Southern analysis	V10 probe
Igh-VJ606	Southern analysis	VJ606 probe
Igh-V12	Southern analysis	V12 probe
Igh-V3609N	Southern analysis	V3909N probe
Igh-V3660	Southern analysis	pRN5.15
Igh-VGAM3.8	Southern analysis	VGAM3.8 genomic
Igh-V11	Southern analysis	V11 probe
Igh-VX24	Southern analysis	VX24 probe
Igh-VSM7	Southern analysis	Igh-VSM7 probe
Igh-VS107	Southern analysis	VS107 probe 2
Igh-VQ52	Southern analysis	VQ52 probe
Igh-V7183	Southern analysis	VhSAPC-15

Notes

• Experiment
  Analysis of CXXB [(BALB/cAnn.xid x C57BL/10)F1] and CXCB [(BALB/cByB x CBA/Tufts)F1] pre-B cell lines yielded a relative chromosomal order of Igh-V genes that is consistant with all observed patterns of Igh-V gene deletion and retention. This data physically mapped the following order of loci on mouse Chromosome 12: Igh-VJ558 - Igh-V3609 - Igh-V15 - Igh-V10 - Igh-VJ606 - Igh-V12 - Igh-V3609N - Igh-V3660 - Igh-VGAM3.8 - Igh-V11 - Igh-VX24 - Igh-VSM7 - Igh-VS107 - Igh-VQ52 - Igh-V7183. Genes within families may not be contiguous in genomic DNA, for example Igh-V3660 genes map to 3 locations within the Igh-V region.