Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  9
• Reference
  J:8783 Prochazka M, et al., Three recessive loci required for insulin-dependent diabetes in nonobese diabetic mice [published erratum appears in Science 1988 Nov 11;242(4880):945]. Science. 1987 Jul 17;237(4812):286-9
• ID
  MGI:46809

Genes

Gene	Assay Type	Description
Idd2	other	lymphocytic infiltration
Apoa1	electrophoretic
Cyp1a2	Southern analysis	pP3450FL
Me1	electrophoretic

Notes

• Reference
  Revised gene symbol: Apoa1 (formerly Alp-1). Cyp1a2 identified as P450-3.
• Experiment
  Thy1 typing used to confirm a position of Idd2 proximal to Thy1.Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, sexes unspecified or combined
• Female Parent
  <d> <d> <d> <d>/<n> <n> <n> <n>
• Strain
  (NOD/Lt x NON/Lt)F1
• Male Parent
  <d> <d> <d> <d>/<d> <d> <d> <d>
• Strain
  NOD/ShiLt
• Allele 1
  d from NOD/ShiLt
• Allele 2
  n from NON/ShiLt

CROSS Data

MC #mice	Idd2	Apoa1	Cyp1a2	Me1
11	d	d	d	d
1	d	n	n	n
3	d	d	n	n
2	d	d	d	n
2	d	n	n	d

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Idd2	Apoa1	3	19	15.789	8.365
Apoa1	Cyp1a2	3	19	15.789	8.365
Cyp1a2	Me1	4	19	21.053	9.353