Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  7
• Reference
  J:10061 Angel JM, et al., Genetics of N-methyl-N-nitrosourea induction of thymic lymphomas in AKR/J mice: assignment of a susceptibility gene to mouse chromosome 7. J Natl Cancer Inst. 1989 Nov 1;81(21):1652-5
• ID
  MGI:46926

Genes

Gene	Allele	Assay Type
Tlag1		visible phenotype
Tyr	Tyr^c	visible phenotype

Notes

• Experiment
  AKR/J mice are susceptible to MNU inducrd thymic lymphoma. The authors indicate that susceptibility is controlled by several genes. In (AKR/J x C57L/J)F2 mice one gene (Tlag1) was shown associated with the albino locus, since 6/6 albinos had tumors, and only 2/27 nonalbinos had tumors. The association of tumor incidence with the albino locus suggests tight linkage of Tlag1 and Tyr^c on mouse Chromosome 7. X² = 17.8 1 df p <.0001.