Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  2
• Reference
  J:32931 Siracusa LD, et al., A tandem duplication within the fibrillin 1 gene is associated with the mouse tight skin mutation. Genome Res. 1996 Apr;6(4):300-13
• ID
  MGI:46945

Genes

Gene	Allele	Assay Type
D2Mit63		reported elsewhere
Fbn1	Fbn1^Tsk	visible phenotype
D2Mit19		reported elsewhere

Notes

• Reference
  Authors show that a tadem duplication within Fbn1 is associated with the Tsk mutant phenotype. This data strongly suggest that Tsk is an allele of Fbn1.

CROSS

• Type
  Backcross, sexes unspecified or combined
• Female Parent
  <c> <c> <c> <c>/<b> <b> <b> <b>
• Strain
  (CAST/EiJ x C57BL/6J-Bloc1s6 +/+ Fbn1)F1
• Male Parent
  <c> <c> <c> <c>/<c> <c> <c> <c>
• Strain
  CAST/EiJ
• Allele 1
  c from CAST/EiJ
• Allele 2
  b from C57BL/6J

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
D2Mit63	D2Mit19	4	128
Fbn1	Fbn1	0	17

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
D2Mit63	D2Mit19	4	132	3.030	1.492
Fbn1	Fbn1	0	17	0.000	0.000