Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  19
• Reference
  J:20807 Keller SA, et al., Kidney and retinal defects (Krd), a transgene-induced mutation with a deletion of mouse chromosome 19 that includes the Pax2 locus. Genomics. 1994 Sep 15;23(2):309-20
• ID
  MGI:47052

Genes

Gene	Allele	Assay Type	Description
Hps1	Hps1^ep	visible phenotype
Del(19)Tg8052Mm		Southern analysis	Del(19)TgN8052Mm clone 1

Notes

• Reference
  Authors use Scd-1, Adrb-1 and Cyp2c for locus symbols Scd1, Adrb1 and Cyp2c29 respectively.
• Experiment
  To test directly for deletion of Hps1^ep, Krd/+ mice were crossed to C57BL/6-ep/ep homozygotes. Three of the 12 offspring had the diluted pigmentation characteristic of pale ears, and 9 were wildtype. The inability of the transgenic choromosome to complement the Hps1^ep mutation is consistent with deletion of Hps1^ep from the transgenic chromosome.