Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  1
• Reference
  J:34785 Christner PJ, et al., A high-resolution linkage map of the tight skin 2 (Tsk2) locus: a mouse model for scleroderma (SSc) and other cutaneous fibrotic diseases. Mamm Genome. 1996 Aug;7(8):610-2
• ID
  MGI:47152

Genes

Gene	Assay Type
Sgk3	visible phenotype
Col3a1	visible phenotype
Mlph	visible phenotype

Notes

• Reference
  Authors state that Col3a1 is a likely candidate gene for Tsk2.

CROSS

• Type
  Backcross, sexes unspecified or combined
• Female Parent
  <f> <f> <f>/<s> <s> <s>
• Strain
  (STOCK Sgk3 + Mlph/+ Col3a1 +)F1
• Male Parent
  <f> <f> <f>/<f> <f> <f>
• Strain
  STOCK Sgk3 + Mlph
• Allele 1
  f from STOCK Sgk3 + Mlph
• Allele 2
  s from STOCK Col3a1

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
Sgk3	Col3a1	28	120
Col3a1	Mlph	30	118

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Sgk3	Col3a1	28	148	18.919	3.219
Col3a1	Mlph	30	148	20.270	3.305