Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  1
• Reference
  J:34785 Christner PJ, et al., A high-resolution linkage map of the tight skin 2 (Tsk2) locus: a mouse model for scleroderma (SSc) and other cutaneous fibrotic diseases. Mamm Genome. 1996 Aug;7(8):610-2
• ID
  MGI:47154

Genes

Gene	Assay Type
Sgk3	visible phenotype
Col3a1	visible phenotype
Dbf	visible phenotype

Notes

• Reference
  Authors state that Col3a1 is a likely candidate gene for Tsk2.
• Experiment
  Authors typed 21 offspring from a (fz + Dbf/+ Tsk2 +)F1 x fz + +/fz + + backcross in order to determine the following order of loci on mouse Chromosome 1: fz 19.0 +/- 8.6 cM - Tsk2 - 19.0 +/- 8.6 cM - Dbf.