Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  4
• Reference
  J:30263 Lee GH, et al., Most liver epithelial cell lines from C3B6F1 mice exhibit parentally-biased loss of heterozygosity at the Lci (Liver cell immortalization) locus on chromosome 4. Oncogene. 1995 Dec 7;11(11):2281-7
• ID
  MGI:47255

Genes

Gene	Assay Type
D4Mit101	PCR amplified length variant
D4Mit39	PCR amplified length variant
D4Mit4	PCR amplified length variant
D4Mit9	PCR amplified length variant
D4Mit31	PCR amplified length variant
D4Mit43	PCR amplified length variant
D4Mit76	PCR amplified length variant
D4Mit52	PCR amplified length variant
D4Mit37	PCR amplified length variant
D4Mit57	PCR amplified length variant
D4Mit12	PCR amplified length variant
Lci	reported elsewhere
D4Mit16	PCR amplified length variant
D4Mit124	PCR amplified length variant
D4Mit125	PCR amplified length variant
D4Mit73	PCR amplified length variant
D4Mit71	PCR amplified length variant
D4Mit54	PCR amplified length variant
D4Mit42	PCR amplified length variant

Notes

• Experiment
  Twenty liver epithelial clonal cell lines, established from (C3H/HeJ x C57BL/6J)F1 mice, were examined for loss of heterozygosity at 19 SRR Mit marker loci on mouse Chromosome 4. The highest incidences of loss of heterozygosity (95%) were observed at D4Mit12, D4Mit37, D4Mit57, D4Mit124 and D4Mit125 indicating that the most likely position for the supressor gene, Lci, is within the interval between D4Mit123 and D4Mit52 or D4Mit76. These data determined the following order of loci on mouse Chromosome 4: D4Mit101 - D4Mit39 - D4Mit4 - D4Mit9 - D4Mit31 - D4Mit43 - D4Mit76 - D4Mit52 - D4Mit37 - D4Mit57 - D4Mit12 - Lci - D4Mit16 - D4Mit124 - D4Mit125 - D4Mit73 - D4Mit71 - D4Mit54 - D4Mit42.