Mapping Data

Experiment

• Experiment
  TEXT-Physical Mapping
• Chromosome
  X
• Reference
  J:33576 Levin ML, et al., A comparative transcription map of the murine bare patches (Bpa) and striated (Str) critical regions and human Xq28. Genome Res. 1996 Jun;6(6):465-77
• ID
  MGI:47741

Genes

Gene	Assay Type	Description
DXHXS1104	overlapping clones	C73E6, B16S5, cosmid 176, cosmid 182
Pwwp4b	overlapping clones	C73E6, B16S5, B20S1, cosmid 181, cosmid 137, P3 P4,
Zfp185	direct sequencing	P1-A cDNA1
Zfp275	overlapping clones	B16S5, B20S1, cosmid 143, cosmid 187, P1
Nsdhl	visible phenotype
Xlr3	Southern analysis	Xlr3b cDNA
F8a	reported elsewhere
Zfp92	direct sequencing	Zfp92 cDNA1
Bgn	reported elsewhere

Notes

• Reference
  Authors use H105e3 and P1A for locus symbols Nsdhl and Zfp185 respectively.
• Experiment
  Mouse genes Bpa (bare patches) and Str (striated) produce clinical features similar to those induced by human genes CDPX2 and Ip2, respectively. In an attempt to isolate genes in the conserved region of mouse Chromosome X, partial physical maps were generated using selected YAC, P1, and cosmid clones. An overlapping 600kb interval between DXHXS1104 and DXHXS52 was proposed to contain the Bpa/Str regions. Str was roughly localized between markers DXHXS1104 and F8a. The Bpa region was estimated to be between ~110kb 3' of DXHXS1104 and DXHXS52. The reported order of other loci in the region was: DXHXS1104 - DXBay18 - Zfp185 - Zfp275 - Nsdhl - Xlr3 - F8a - Zfp92 - Bgn.