Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  10
• Reference
  J:36348 Guay-Woodford LM, et al., Evidence that two phenotypically distinct mouse PKD mutations, bpk and jcpk, are allelic. Kidney Int. 1996 Oct;50(4):1158-65
• ID
  MGI:47877

Genes

Gene	Allele	Assay Type
Bicc1	Bicc1^jcpk-bpk	visible phenotype

Notes

• Reference
  Authors map bpk in close vicinity to jcpk but state that they are currently unable to determine whether the jcpk phenotype results from disruptions in the same locus as bpk or whether it involves two closely linked genes, one of which is bpk.
• Experiment
  An end-mapping strategy was applied to localize Bicc1. Chromosomal haplotypes generated by typing only markers at the ends of each chromosome of ((BALB/c - +/bpk) x CAST/Ei)F1 intercross mutant progeny indicated linage to mouse Chromosome 10. These progenypresented a significant paucity of the apparently non-recombinant CAST/Ei (wild type) haplotype on this chromosome.