Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  10
• Reference
  J:34619 Kapfhamer D, et al., The neurological mouse mutations jittery and hesitant are allelic and map to the region of mouse chromosome 10 homologous to 19p13.3. Genomics. 1996 Aug 1;35(3):533-8
• ID
  MGI:47887

Genes

Gene	Assay Type	Description
D10Mit158	PCR amplified length variant
D10Mit175	PCR amplified length variant
D10Mit207	PCR amplified length variant
Bsg	reported elsewhere
Atcay	visible phenotype
Amh	reported elsewhere
D10Mit7	PCR amplified length variant
D10Mit23	PCR amplified length variant
D10Mit42	PCR amplified length variant
D10Mit140	PCR amplified length variant
Nfyb	Southern analysis	YB-EM38
D10Mit160	PCR amplified length variant

Notes

• Reference
  Heterozygotes for hesitant (C3H-hes/+) and jittery (JIGR/Dn- ji +/+ gr) were mated with each other. Of 32 offspring, 12 clearly had the hesitant phenotype. This result established non-complementation of the two mutations. Cross mapping data which indicated co-localization of hes and ji on mouse Chromosome 10 established that hesitant and jittery are caused by mutant alleles of the same gene.
• Experiment
  An intersubspecific backcross of JIGR/Dn-gr +/+ ji mice with CAST/Ei was carried out. Only F1 animals carrying a ji/+ genotype (as determined by a test cross) were used to generate the F2 cross. All animals from this cross (affected and unaffected), werescored. 57 progeny reported here were from a backcross and 116 from an intercross providing a total of 289 chromosomes analyzed.Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Other
• Female Parent
  <j> <j> <j> <j> <j> <j> <j> <j> <j> <j> <j> <j>/<c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c>
• Strain
  (JIGR/Dn Mfsd12 +/+ Atcay x CAST/Ei)F1-Atcay
• Male Parent
  <j> <j> <j> <j> <j> <j> <j> <j> <j> <j> <j> <j>/<c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c>
• Strain
  (JIGR/Dn Mfsd12 +/+ Atcay x CAST/Ei)F1-Atcay
• Allele 1
  j from JIGR/DnJ
• Allele 2
  c from CAST/EiJ

CROSS Data

MC #mice	D10Mit158	D10Mit175	D10Mit207	Bsg	Atcay	Amh	D10Mit7	D10Mit23	D10Mit42	D10Mit140	Nfyb	D10Mit160
137	j	.	.	.	j	j	j	j	.	.	.	j
139	c	.	.	.	c	c	c	c	.	.	.	c
2	c	j	j	j	j	j	j	j	j	j	j	j
2	j	c	c	c	c	c	c	c	c	c	c	c
1	c	c	j	j	j	j	j	j	j	j	j	j
0	j	j	c	c	c	c	c	c	c	c	c	c
1	c	c	c	j	j	j	j	j	j	j	j	j
0	j	j	j	c	c	c	c	c	c	c	c	c
1	c	c	c	c	j	j	j	j	j	j	j	j
0	j	j	j	j	c	c	c	c	c	c	c	c
1	c	c	c	c	c	c	c	c	j	j	j	j
2	j	j	j	j	j	j	j	j	c	c	c	c
2	c	c	c	c	c	c	c	c	c	c	c	j
1	j	j	j	j	j	j	j	j	j	j	j	c