Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  10
• Reference
  J:34619 Kapfhamer D, et al., The neurological mouse mutations jittery and hesitant are allelic and map to the region of mouse chromosome 10 homologous to 19p13.3. Genomics. 1996 Aug 1;35(3):533-8
• ID
  MGI:47888

Genes

Gene	Allele	Assay Type
D10Mit115		PCR amplified length variant
Atcay	Atcay^ji-hes	visible phenotype
D10Mit42		PCR amplified length variant
D10Mit10		reported elsewhere

Notes

• Reference
  Heterozygotes for hesitant (C3H-hes/+) and jittery (JIGR/Dn- ji +/+ gr) were mated with each other. Of 32 offspring, 12 clearly had the hesitant phenotype. This result established non-complementation of the two mutations. Cross mapping data which indicated co-localization of hes and ji on mouse Chromosome 10 established that hesitant and jittery are caused by mutant alleles of the same gene.
• Experiment
  Data for the D10Mit10 marker is not shown, the distance between ji^hes, D10Mit42 and D10Mit10 is reported to be 12.5 +/- 6.6 cM.Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Intercross
• Female Parent
  <c> <c> <c>/<b> <b> <b>
• Strain
  (C3HeB/FeJ-Atcay x C57BL/6J)F1
• Male Parent
  <c> <c> <c>/<b> <b> <b>
• Strain
  (C3HeB/FeJ-Atcay x C57BL/6J)F1
• Allele 1
  c from C3H-Atcay/J
• Allele 2
  b from C57BL/6J

CROSS Data

MC #mice	D10Mit115	Atcay	D10Mit42	D10Mit10
171	c	c	c
3	b	c	c
0	c	c	b