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Mapping Data
Experiment
  • Experiment
    TEXT-QTL
  • Chromosome
    18
  • Reference
    J:36219 Obata M, et al., Identification of the Par2 (Pulmonary adenoma resistance) locus on mouse chromosome 18, a major genetic determinant for lung carcinogen resistance in BALB/cByJ mice. Oncogene. 1996 Oct 17;13(8):1599-604
  • ID
    MGI:47943
Genes
GeneAlleleAssay TypeDescription
Par2 resistance/susceptibility
D18Mit103 PCR amplified length variant
Notes
  • Experiment
    One hundred thirty (A/JSlc x BALB/cByJJcl)F1 x A/JSlc backcross mice exhibiting extremes of tumor multiplicity after i.p. injection of urethane were genotyped for 63 simple sequence repeat (SSR) loci.

    Statistical analysis indicated significant linkage of the tumor resistance gene (Par2) to mouse Chromosome 18, primarily at the D18Mit103 locus with a maximun LOD score of 12 (p<0.000001).

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory