Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  7
• Reference
  J:37678 Grosson CL, et al., Sequence of the voltage-gated sodium channel beta1-subunit in wild-type and in quivering mice. Brain Res Mol Brain Res. 1996 Dec;42(2):222-6
• ID
  MGI:47997

Genes

Gene	Allele	Assay Type
Scn1b		direct sequencing
Sptbn4	Sptbn4^qv-J	visible phenotype

Notes

• Experiment
  Direct sequencing of the Scn1b coding region within C57BL/6J, C3HeB/FeJ, 129/SvJ, BALB/c, DBA/2J and Spnb4^qv-J/Spnb4^qv-J mice identified single base pair polymorphism between these strains. The derivation of the Spnb4^qv-J phenotype animals was considered, and enabled the authors to show that the DBA/2J allele of Scn1b segregated on mouse Chromosome 7 with the Spnb4^qv-J/Spnb4^qv-J (Hope Sweet, The Jackson Laboratory, personal communication). The authors indicated, however, that the Scn1b protein was not the cause of the ^qv-J effect in mice.