Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  2
• Reference
  J:36997 Fijneman RJ, et al., Complex interactions of new quantitative trait loci, Sluc1, Sluc2, Sluc3, and Sluc4, that influence the susceptibility to lung cancer in the mouse. Nat Genet. 1996 Dec;14(4):465-7
• ID
  MGI:48005

Genes

Gene	Assay Type
D2Mit7	PCR amplified length variant
D2Mit156	PCR amplified length variant
D2Mit56	PCR amplified length variant
Sluc2	resistance/susceptibility

Notes

• Experiment
  Lung tissue of N-ethyl-N-nitrosourea treated F2 progeny of an (OcB-9/Dem x O20/A)F1 intercross was microscopically analyzed for the presence and size of tumors. The progeny were genotyped by PCR. Statistical analysis indicated the presence of a locus influencing susceptibility to lung cancer (Sluc2) on mouse Chromosome 2. The QTL likelihood plot indicates a peak near D2Mit56. The following order of loci was reported: D2Mit7 - D2Mit156 - D2Mit56 - Sluc2.