Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  6
• Reference
  J:36997 Fijneman RJ, et al., Complex interactions of new quantitative trait loci, Sluc1, Sluc2, Sluc3, and Sluc4, that influence the susceptibility to lung cancer in the mouse. Nat Genet. 1996 Dec;14(4):465-7
• ID
  MGI:48006

Genes

Gene	Assay Type
D6Mit21	PCR amplified length variant
D6Mit36	PCR amplified length variant
Sluc3	resistance/susceptibility
D6Mit218	PCR amplified length variant
D6Mit52	PCR amplified length variant
Kras	reported elsewhere

Notes

• Experiment
  Lung tissue of N-ethyl-N-nitrosourea treated F2 progeny of an (OcB-9/Dem x O20/A)F1 intercross was microscopically analyzed for the presence and size of tumors. The progeny were genotyped by PCR. Statistical analysis indicated the presence of a locus influencing susceptibility to lung cancer (Sluc3) on mouse Chromosome 6. The QTL likelihood plot indicates a peak between D2Mit36 and D6Mit218, proximal to the Kras2 locus. The following order of loci was reported: D6Mit21 - D6Mit36 - Sluc3 - D6Mit218 - D6mMit52 - Kras.