Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  19
• Reference
  J:36997 Fijneman RJ, et al., Complex interactions of new quantitative trait loci, Sluc1, Sluc2, Sluc3, and Sluc4, that influence the susceptibility to lung cancer in the mouse. Nat Genet. 1996 Dec;14(4):465-7
• ID
  MGI:48008

Genes

Gene	Assay Type
D19Mit42	reported elsewhere
D19Mit61	PCR amplified length variant
D19Mit63	PCR amplified length variant
D19Mit19	reported elsewhere
Sluc1	resistance/susceptibility
D19Mit9	PCR amplified length variant
D19Mit33	PCR amplified length variant

Notes

• Experiment
  Lung tissue of N-ethyl-N-nitrosourea treated F2 progeny of an (OcB9/Dem x O20/A)F1 intercross was microscopically analyzed for the presence and size of tumors. The progeny were genotyped by PCR. Statistical analysis indicated the presence of a locus influencing susceptibility to lung cancer (Sluc1) on mouse Chromosome 19, distal to the Pas3 region (flanked by D19Mit42 and D19Mit19). The QTL likelihood plot indicates a peak near D19Mit9. The following order of loci was reported: D19Mit42 - D19Mit61- D19Mit63 - D19Mit19 - Sluc1 - D19Mit9 - D19Mit33.