Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  3
• Reference
  J:34178 Welch CL, et al., Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes. J Lipid Res. 1996 Jul;37(7):1406-21
• ID
  MGI:48081

Genes

Gene	Assay Type	Description
D3Mit23	PCR amplified length variant
D3Ucla3	reported elsewhere
D3Mit21	PCR amplified length variant
D3Ucla4	reported elsewhere
Serp1	reported elsewhere
D3Mit9	PCR amplified length variant
D3Ucla2	reported elsewhere
Fgg	reported elsewhere
Fdps	Southern analysis	pFPPS-0.69
Arnt	reported elsewhere
Hmgcs2	Southern analysis	PmitsynF, PmitsynR
D3Ucla5	reported elsewhere
F3	reported elsewhere
D3Mit16	PCR amplified length variant
D3Mit18	PCR amplified length variant
D3Mit19	PCR amplified length variant

Notes

• Reference
  The marker maps experimentally derived in this paper were overlapped with published maps for a number of QTL regions associated with plasma total cholesterol (Chromosomes 1, 5, 6, 7, 12, 15 ,18), plasma HDL cholesterol (Chromosomes 1, 5, 7, 17), plasma LDL/VLDL cholesterol (Chromosomes 9, 12, 13, 15), plasma triglyceride (Chromosomes 5, 7), gallstones (Chromosome 2), and obesity (Chromosomes 4, 6, 7, 9, 12, 15). Authors use Lipc, Brn3.1, Ghrhrr, Gad-1ps, Otf11, Sel1, Tcfcoup2, Crfr, Brn5.0, G6pd, Otf9, Igl1, Pgs1, Lgals1 and Lgals2 for locus symbols Hpl, Pou4f3, Ghrhr, Gad1-ps, Pou2f3, DSell, Aporp1, Crhr, Pou6f1, G6pdx, Pou3f4, Igl-5, Ptgs1, Lgals4 and Lgals6 respectively.

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  UCLA (BSB)
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
D3Mit23	D3Ucla3	1	60
D3Ucla3	D3Mit21	1	60
D3Mit21	D3Ucla4	4	57
D3Ucla4	Serp1	3	62
Serp1	D3Mit9	2	60
D3Mit9	D3Ucla2	4	56
D3Ucla2	Fgg	3	60
Fgg	Fdps	3	62
Fdps	Arnt	3	63
Arnt	Hmgcs2	3	63
Hmgcs2	D3Ucla5	2	63
D3Ucla5	F3	1	64
F3	D3Mit16	7	87
D3Mit16	D3Mit18	1	59
D3Mit18	D3Mit19	4	56

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
D3Mit23	D3Ucla3	1	61	1.639	1.626
D3Ucla3	D3Mit21	1	61	1.639	1.626
D3Mit21	D3Ucla4	4	61	6.557	3.169
D3Ucla4	Serp1	3	65	4.615	2.602
Serp1	D3Mit9	2	62	3.226	2.244
D3Mit9	D3Ucla2	4	60	6.667	3.220
D3Ucla2	Fgg	3	63	4.762	2.683
Fgg	Fdps	3	65	4.615	2.602
Fdps	Arnt	3	66	4.545	2.564
Arnt	Hmgcs2	3	66	4.545	2.564
Hmgcs2	D3Ucla5	2	65	3.077	2.142
D3Ucla5	F3	1	65	1.538	1.527
F3	D3Mit16	7	94	7.447	2.708
D3Mit16	D3Mit18	1	60	1.667	1.653
D3Mit18	D3Mit19	4	60	6.667	3.220