Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  6
• Reference
  J:34178 Welch CL, et al., Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes. J Lipid Res. 1996 Jul;37(7):1406-21
• ID
  MGI:48084

Genes

Gene	Assay Type
Fdpsl10	reported elsewhere
D6Mit1	PCR amplified length variant
Pon1	reported elsewhere
D6Mit48	PCR amplified length variant
D6Nds4	reported elsewhere
D6Ucla2	reported elsewhere
Ghrhr	reported elsewhere
D6Mit17	PCR amplified length variant
D6Mit8	PCR amplified length variant
Cnbpl2	reported elsewhere
D6Nds5	reported elsewhere
Pparg	reported elsewhere
Adipor2	reported elsewhere
D6Mit12	PCR amplified length variant
Eno2	reported elsewhere

Notes

• Reference
  The marker maps experimentally derived in this paper were overlapped with published maps for a number of QTL regions associated with plasma total cholesterol (Chromosomes 1, 5, 6, 7, 12, 15 ,18), plasma HDL cholesterol (Chromosomes 1, 5, 7, 17), plasma LDL/VLDL cholesterol (Chromosomes 9, 12, 13, 15), plasma triglyceride (Chromosomes 5, 7), gallstones (Chromosome 2), and obesity (Chromosomes 4, 6, 7, 9, 12, 15). Authors use Lipc, Brn3.1, Ghrhrr, Gad-1ps, Otf11, Sel1, Tcfcoup2, Crfr, Brn5.0, G6pd, Otf9, Igl1, Pgs1, Lgals1 and Lgals2 for locus symbols Hpl, Pou4f3, Ghrhr, Gad1-ps, Pou2f3, DSell, Aporp1, Crhr, Pou6f1, G6pdx, Pou3f4, Igl-5, Ptgs1, Lgals4 and Lgals6 respectively.

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  UCLA (BSB)
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
Fdpsl10	D6Mit1	0	57
Fdpsl10	Pon1	0	57
D6Mit1	Pon1	0	57
Fdpsl10	D6Mit48	2	56
D6Mit1	D6Mit48	2	56
Pon1	D6Mit48	2	56
D6Mit48	D6Nds4	9	56
D6Nds4	D6Ucla2	4	62
D6Nds4	Ghrhr	4	62
D6Ucla2	D6Mit17	3	56
Ghrhr	D6Mit17	3	56
D6Mit17	D6Mit8	7	52
D6Mit8	Cnbpl2	3	63
Cnbpl2	D6Nds5	6	59
D6Nds5	Pparg	4	61
Pparg	Adipor2	1	65
Pparg	D6Mit12	1	65
Adipor2	D6Mit12	0	51
Adipor2	Eno2	1	50
D6Mit12	Eno2	1	50

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Fdpsl10	D6Mit1	0	57	0.000	0.000
Fdpsl10	Pon1	0	57	0.000	0.000
D6Mit1	Pon1	0	57	0.000	0.000
Fdpsl10	D6Mit48	2	58	3.448	2.396
D6Mit1	D6Mit48	2	58	3.448	2.396
Pon1	D6Mit48	2	58	3.448	2.396
D6Mit48	D6Nds4	9	65	13.846	4.284
D6Nds4	D6Ucla2	4	66	6.061	2.937
D6Nds4	Ghrhr	4	66	6.061	2.937
D6Ucla2	D6Mit17	3	59	5.085	2.860
Ghrhr	D6Mit17	3	59	5.085	2.860
D6Mit17	D6Mit8	7	59	11.864	4.210
D6Mit8	Cnbpl2	3	66	4.545	2.564
Cnbpl2	D6Nds5	6	65	9.231	3.590
D6Nds5	Pparg	4	65	6.154	2.981
Pparg	Adipor2	1	66	1.515	1.504
Pparg	D6Mit12	1	66	1.515	1.504
Adipor2	D6Mit12	0	51	0.000	0.000
Adipor2	Eno2	1	51	1.961	1.941
D6Mit12	Eno2	1	51	1.961	1.941