Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  10
• Reference
  J:34178 Welch CL, et al., Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes. J Lipid Res. 1996 Jul;37(7):1406-21
• ID
  MGI:48087

Genes

Gene	Assay Type	Description
D10Ucla3	reported elsewhere
Pcmt1	reported elsewhere
D10Mit2	PCR amplified length variant
Myb	reported elsewhere
Aco2	reported elsewhere
D10Ucla4	reported elsewhere
D10Mit20	PCR amplified length variant
Reep3	reported elsewhere
Rrm2-ps4	reported elsewhere
D10Mit7	PCR amplified length variant
D10Ucla5	reported elsewhere
Pah	reported elsewhere
D10Mit10	PCR amplified length variant
D10Ucla6	reported elsewhere
Gad1-ps	reported elsewhere
D10Mit24	PCR amplified length variant
Lrp-rs	Southern analysis	pLRP2
D10Ucla7	reported elsewhere
Apon	reported elsewhere
Prim1	reported elsewhere

Notes

• Reference
  The marker maps experimentally derived in this paper were overlapped with published maps for a number of QTL regions associated with plasma total cholesterol (Chromosomes 1, 5, 6, 7, 12, 15 ,18), plasma HDL cholesterol (Chromosomes 1, 5, 7, 17), plasma LDL/VLDL cholesterol (Chromosomes 9, 12, 13, 15), plasma triglyceride (Chromosomes 5, 7), gallstones (Chromosome 2), and obesity (Chromosomes 4, 6, 7, 9, 12, 15). Authors use Lipc, Brn3.1, Ghrhrr, Gad-1ps, Otf11, Sel1, Tcfcoup2, Crfr, Brn5.0, G6pd, Otf9, Igl1, Pgs1, Lgals1 and Lgals2 for locus symbols Hpl, Pou4f3, Ghrhr, Gad1-ps, Pou2f3, DSell, Aporp1, Crhr, Pou6f1, G6pdx, Pou3f4, Igl-5, Ptgs1, Lgals4 and Lgals6 respectively.

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  UCLA (BSB)
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
D10Ucla3	Pcmt1	2	64
Pcmt1	D10Mit2	3	40
Pcmt1	Myb	3	40
D10Mit2	Myb	0	39
Myb	Aco2	1	59
Aco2	D10Ucla4	1	65
D10Ucla4	D10Mit20	7	58
D10Mit20	Reep3	1	64
Reep3	Rrm2-ps4	3	63
Reep3	D10Mit7	3	63
Reep3	D10Ucla5	3	63
Rrm2-ps4	D10Mit7	0	64
Rrm2-ps4	D10Ucla5	0	64
D10Mit7	D10Ucla5	0	64
Rrm2-ps4	Pah	7	56
D10Mit7	Pah	7	56
D10Ucla5	Pah	7	56
Pah	D10Mit10	1	62
D10Mit10	D10Ucla6	8	57
D10Mit10	Gad1-ps	8	57
D10Ucla6	Gad1-ps	0	65
D10Ucla6	D10Mit24	6	57
Gad1-ps	D10Mit24	6	53
D10Mit24	Lrp-rs	3	61
Lrp-rs	D10Ucla7	2	64
Lrp-rs	Apon	2	64
Lrp-rs	Prim1	2	64
D10Ucla7	Apon	0	66
D10Ucla7	Prim1	0	66
Apon	Prim1	0	66

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
D10Ucla3	Pcmt1	2	66	3.030	2.110
Pcmt1	D10Mit2	3	43	6.977	3.885
Pcmt1	Myb	3	43	6.977	3.885
D10Mit2	Myb	0	39	0.000	0.000
Myb	Aco2	1	60	1.667	1.653
Aco2	D10Ucla4	1	66	1.515	1.504
D10Ucla4	D10Mit20	7	65	10.769	3.845
D10Mit20	Reep3	1	65	1.538	1.527
Reep3	Rrm2-ps4	3	66	4.545	2.564
Reep3	D10Mit7	3	66	4.545	2.564
Reep3	D10Ucla5	3	66	4.545	2.564
Rrm2-ps4	D10Mit7	0	64	0.000	0.000
Rrm2-ps4	D10Ucla5	0	64	0.000	0.000
D10Mit7	D10Ucla5	0	64	0.000	0.000
Rrm2-ps4	Pah	7	63	11.111	3.959
D10Mit7	Pah	7	63	11.111	3.959
D10Ucla5	Pah	7	63	11.111	3.959
Pah	D10Mit10	1	63	1.587	1.575
D10Mit10	D10Ucla6	8	65	12.308	4.075
D10Mit10	Gad1-ps	8	65	12.308	4.075
D10Ucla6	Gad1-ps	0	65	0.000	0.000
D10Ucla6	D10Mit24	6	63	9.524	3.698
Gad1-ps	D10Mit24	6	59	10.169	3.935
D10Mit24	Lrp-rs	3	64	4.688	2.642
Lrp-rs	D10Ucla7	2	66	3.030	2.110
Lrp-rs	Apon	2	66	3.030	2.110
Lrp-rs	Prim1	2	66	3.030	2.110
D10Ucla7	Apon	0	66	0.000	0.000
D10Ucla7	Prim1	0	66	0.000	0.000
Apon	Prim1	0	66	0.000	0.000