Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  11
• Reference
  J:34178 Welch CL, et al., Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes. J Lipid Res. 1996 Jul;37(7):1406-21
• ID
  MGI:48088

Genes

Gene	Assay Type
D11Mit1	PCR amplified length variant
Sptbn1	reported elsewhere
D11Mit51	PCR amplified length variant
D11Ucla3	reported elsewhere
D11Mit24	PCR amplified length variant
D11Mit26	PCR amplified length variant
Eno3	reported elsewhere
Lgals9	reported elsewhere
D11Mit34	PCR amplified length variant
Nos2	reported elsewhere
D11Ucla1	reported elsewhere
Ccl2	reported elsewhere
D11Mit59	PCR amplified length variant
Crhr1	reported elsewhere
Prkca	reported elsewhere
D11Ucla2	reported elsewhere
D11Mit11	PCR amplified length variant

Notes

• Reference
  The marker maps experimentally derived in this paper were overlapped with published maps for a number of QTL regions associated with plasma total cholesterol (Chromosomes 1, 5, 6, 7, 12, 15 ,18), plasma HDL cholesterol (Chromosomes 1, 5, 7, 17), plasma LDL/VLDL cholesterol (Chromosomes 9, 12, 13, 15), plasma triglyceride (Chromosomes 5, 7), gallstones (Chromosome 2), and obesity (Chromosomes 4, 6, 7, 9, 12, 15). Authors use Lipc, Brn3.1, Ghrhrr, Gad-1ps, Otf11, Sel1, Tcfcoup2, Crfr, Brn5.0, G6pd, Otf9, Igl1, Pgs1, Lgals1 and Lgals2 for locus symbols Hpl, Pou4f3, Ghrhr, Gad1-ps, Pou2f3, DSell, Aporp1, Crhr, Pou6f1, G6pdx, Pou3f4, Igl-5, Ptgs1, Lgals4 and Lgals6 respectively.

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  UCLA (BSB)
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
D11Mit1	Sptbn1	6	53
Sptbn1	D11Mit51	4	56
D11Mit51	D11Ucla3	7	58
D11Ucla3	D11Mit24	1	63
D11Mit24	D11Mit26	2	63
D11Mit26	Eno3	5	61
Eno3	Lgals9	3	62
Lgals9	D11Mit34	1	60
Lgals9	Nos2	1	60
Lgals9	D11Ucla1	1	60
D11Mit34	Nos2	0	6
D11Mit34	D11Ucla1	0	6
Nos2	D11Ucla1	0	6
D11Mit34	Ccl2	2	63
Nos2	Ccl2	2	63
D11Ucla1	Ccl2	2	63
Ccl2	D11Mit59	13	51
D11Mit59	Crhr1	1	60
Crhr1	Prkca	2	60
Prkca	D11Ucla2	1	62
D11Ucla2	D11Mit11	2	51

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
D11Mit1	Sptbn1	6	59	10.169	3.935
Sptbn1	D11Mit51	4	60	6.667	3.220
D11Mit51	D11Ucla3	7	65	10.769	3.845
D11Ucla3	D11Mit24	1	64	1.562	1.550
D11Mit24	D11Mit26	2	65	3.077	2.142
D11Mit26	Eno3	5	66	7.576	3.257
Eno3	Lgals9	3	65	4.615	2.602
Lgals9	D11Mit34	1	61	1.639	1.626
Lgals9	Nos2	1	61	1.639	1.626
Lgals9	D11Ucla1	1	61	1.639	1.626
D11Mit34	Nos2	0	6	0.000	0.000
D11Mit34	D11Ucla1	0	6	0.000	0.000
Nos2	D11Ucla1	0	6	0.000	0.000
D11Mit34	Ccl2	2	65	3.077	2.142
Nos2	Ccl2	2	65	3.077	2.142
D11Ucla1	Ccl2	2	65	3.077	2.142
Ccl2	D11Mit59	13	64	20.312	5.029
D11Mit59	Crhr1	1	61	1.639	1.626
Crhr1	Prkca	2	62	3.226	2.244
Prkca	D11Ucla2	1	63	1.587	1.575
D11Ucla2	D11Mit11	2	53	3.774	2.617