Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  15
• Reference
  J:34178 Welch CL, et al., Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes. J Lipid Res. 1996 Jul;37(7):1406-21
• ID
  MGI:48092

Genes

Gene	Assay Type	Description
Selenop	reported elsewhere
Ghr	reported elsewhere
D15Mit13	PCR amplified length variant
D15Mit10	PCR amplified length variant
D15Mit6	PCR amplified length variant
D15Ucla4	reported elsewhere
D15Mit89	PCR amplified length variant
D15Ucla2	reported elsewhere
Tef	reported elsewhere
Srebf2	Southern analysis	pSREBP-2
D15Mit31	PCR amplified length variant
Ppara	reported elsewhere
D15Ucla3	reported elsewhere
Pou6f1	reported elsewhere
D15Mit16	PCR amplified length variant
Glycam1	reported elsewhere

Notes

• Reference
  The marker maps experimentally derived in this paper were overlapped with published maps for a number of QTL regions associated with plasma total cholesterol (Chromosomes 1, 5, 6, 7, 12, 15 ,18), plasma HDL cholesterol (Chromosomes 1, 5, 7, 17), plasma LDL/VLDL cholesterol (Chromosomes 9, 12, 13, 15), plasma triglyceride (Chromosomes 5, 7), gallstones (Chromosome 2), and obesity (Chromosomes 4, 6, 7, 9, 12, 15). Authors use Lipc, Brn3.1, Ghrhrr, Gad-1ps, Otf11, Sel1, Tcfcoup2, Crfr, Brn5.0, G6pd, Otf9, Igl1, Pgs1, Lgals1 and Lgals2 for locus symbols Hpl, Pou4f3, Ghrhr, Gad1-ps, Pou2f3, DSell, Aporp1, Crhr, Pou6f1, G6pdx, Pou3f4, Igl-5, Ptgs1, Lgals4 and Lgals6 respectively.

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  UCLA (BSB)
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
Selenop	Ghr	0	66
Selenop	D15Mit13	0	66
Ghr	D15Mit13	0	66
Selenop	D15Mit10	2	63
Ghr	D15Mit10	2	63
D15Mit13	D15Mit10	2	63
D15Mit10	D15Mit6	4	53
D15Mit6	D15Ucla4	14	42
D15Ucla4	D15Mit89	3	60
D15Mit89	D15Ucla2	3	60
D15Mit89	Tef	3	60
D15Ucla2	Tef	0	65
D15Ucla2	Srebf2	1	61
D15Ucla2	D15Mit31	1	61
Tef	D15Mit31	1	61
Tef	Srebf2	1	61
Srebf2	D15Mit31	0	65
Srebf2	Ppara	2	54
D15Mit31	Ppara	2	54
Ppara	D15Ucla3	6	59
Ppara	Pou6f1	6	59
D15Ucla3	D15Mit16	1	65
Pou6f1	D15Mit16	1	65
D15Mit16	Glycam1	2	64

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Selenop	Ghr	0	66	0.000	0.000
Selenop	D15Mit13	0	66	0.000	0.000
Ghr	D15Mit13	0	66	0.000	0.000
Selenop	D15Mit10	2	65	3.077	2.142
Ghr	D15Mit10	2	65	3.077	2.142
D15Mit13	D15Mit10	2	65	3.077	2.142
D15Mit10	D15Mit6	4	57	7.018	3.383
D15Mit6	D15Ucla4	14	56	25.000	5.786
D15Ucla4	D15Mit89	3	63	4.762	2.683
D15Mit89	D15Ucla2	3	63	4.762	2.683
D15Mit89	Tef	3	63	4.762	2.683
D15Ucla2	Tef	0	65	0.000	0.000
D15Ucla2	Srebf2	1	62	1.613	1.600
D15Ucla2	D15Mit31	1	62	1.613	1.600
Tef	D15Mit31	1	62	1.613	1.600
Tef	Srebf2	1	62	1.613	1.600
Srebf2	D15Mit31	0	65	0.000	0.000
Srebf2	Ppara	2	56	3.571	2.480
D15Mit31	Ppara	2	56	3.571	2.480
Ppara	D15Ucla3	6	65	9.231	3.590
Ppara	Pou6f1	6	65	9.231	3.590
D15Ucla3	D15Mit16	1	66	1.515	1.504
Pou6f1	D15Mit16	1	66	1.515	1.504
D15Mit16	Glycam1	2	66	3.030	2.110