Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  18
• Reference
  J:34178 Welch CL, et al., Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes. J Lipid Res. 1996 Jul;37(7):1406-21
• ID
  MGI:48095

Genes

Gene	Assay Type
D18Mit14	PCR amplified length variant
Slc23a1	reported elsewhere
D18Ucla1	reported elsewhere
D18Ucla5	reported elsewhere
Cdo1	reported elsewhere
Pou4f3	reported elsewhere
D18Ucla4	reported elsewhere
D18Mit9	PCR amplified length variant
D18Mit33	PCR amplified length variant
D18Mit7	PCR amplified length variant
D18Nds1	reported elsewhere
D18Mit3	PCR amplified length variant
D18Mit25	PCR amplified length variant

Notes

• Reference
  The marker maps experimentally derived in this paper were overlapped with published maps for a number of QTL regions associated with plasma total cholesterol (Chromosomes 1, 5, 6, 7, 12, 15 ,18), plasma HDL cholesterol (Chromosomes 1, 5, 7, 17), plasma LDL/VLDL cholesterol (Chromosomes 9, 12, 13, 15), plasma triglyceride (Chromosomes 5, 7), gallstones (Chromosome 2), and obesity (Chromosomes 4, 6, 7, 9, 12, 15). Authors use Lipc, Brn3.1, Ghrhrr, Gad-1ps, Otf11, Sel1, Tcfcoup2, Crfr, Brn5.0, G6pd, Otf9, Igl1, Pgs1, Lgals1 and Lgals2 for locus symbols Hpl, Pou4f3, Ghrhr, Gad1-ps, Pou2f3, DSell, Aporp1, Crhr, Pou6f1, G6pdx, Pou3f4, Igl-5, Ptgs1, Lgals4 and Lgals6 respectively.

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  UCLA (BSB)
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
D18Mit14	Slc23a1	0	66
D18Mit14	D18Ucla1	1	65
Slc23a1	D18Ucla1	1	65
D18Ucla1	D18Ucla5	3	62
D18Ucla5	Cdo1	1	60
D18Ucla5	Pou4f3	1	60
Cdo1	Pou4f3	0	59
Cdo1	D18Ucla4	9	54
Pou4f3	D18Ucla4	9	54
D18Ucla4	D18Mit9	5	56
D18Mit9	D18Mit33	2	59
D18Mit33	D18Mit7	3	62
D18Mit7	D18Nds1	3	54
D18Mit7	D18Mit3	3	54
D18Nds1	D18Mit3	0	57
D18Nds1	D18Mit25	7	59
D18Mit3	D18Mit25	7	59

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
D18Mit14	Slc23a1	0	66	0.000	0.000
D18Mit14	D18Ucla1	1	66	1.515	1.504
Slc23a1	D18Ucla1	1	66	1.515	1.504
D18Ucla1	D18Ucla5	3	65	4.615	2.602
D18Ucla5	Cdo1	1	61	1.639	1.626
D18Ucla5	Pou4f3	1	61	1.639	1.626
Cdo1	Pou4f3	0	59	0.000	0.000
Cdo1	D18Ucla4	9	63	14.286	4.409
Pou4f3	D18Ucla4	9	63	14.286	4.409
D18Ucla4	D18Mit9	5	61	8.197	3.512
D18Mit9	D18Mit33	2	61	3.279	2.280
D18Mit33	D18Mit7	3	65	4.615	2.602
D18Mit7	D18Nds1	3	57	5.263	2.958
D18Mit7	D18Mit3	3	57	5.263	2.958
D18Nds1	D18Mit3	0	57	0.000	0.000
D18Nds1	D18Mit25	7	66	10.606	3.790
D18Mit3	D18Mit25	7	66	10.606	3.790