Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  19
• Reference
  J:34178 Welch CL, et al., Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes. J Lipid Res. 1996 Jul;37(7):1406-21
• ID
  MGI:48096

Genes

Gene	Assay Type	Description
Fth1	reported elsewhere
Vldlr	Southern analysis	pLRP1
D19Ucla2	reported elsewhere
D19Ucla3	reported elsewhere
D19Mit29	PCR amplified length variant
D19Mit31	PCR amplified length variant
D19Ucla4	reported elsewhere
D19Mit14	PCR amplified length variant
D19Mit12	PCR amplified length variant
D19Ucla5	reported elsewhere
Pdcd4	reported elsewhere
D19Mit4	PCR amplified length variant
D19Mit1	PCR amplified length variant
Pnlip	reported elsewhere
Pnliprp1	reported elsewhere
D19Mit6	PCR amplified length variant

Notes

• Reference
  The marker maps experimentally derived in this paper were overlapped with published maps for a number of QTL regions associated with plasma total cholesterol (Chromosomes 1, 5, 6, 7, 12, 15 ,18), plasma HDL cholesterol (Chromosomes 1, 5, 7, 17), plasma LDL/VLDL cholesterol (Chromosomes 9, 12, 13, 15), plasma triglyceride (Chromosomes 5, 7), gallstones (Chromosome 2), and obesity (Chromosomes 4, 6, 7, 9, 12, 15). Authors use Lipc, Brn3.1, Ghrhrr, Gad-1ps, Otf11, Sel1, Tcfcoup2, Crfr, Brn5.0, G6pd, Otf9, Igl1, Pgs1, Lgals1 and Lgals2 for locus symbols Hpl, Pou4f3, Ghrhr, Gad1-ps, Pou2f3, DSell, Aporp1, Crhr, Pou6f1, G6pdx, Pou3f4, Igl-5, Ptgs1, Lgals4 and Lgals6 respectively.

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  UCLA (BSB)
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
Fth1	Vldlr	1	66
Fth1	D19Ucla2	1	66
Fth1	D19Ucla3	1	66
Vldlr	D19Ucla2	0	65
Vldlr	D19Ucla3	0	65
D19Ucla2	D19Ucla3	0	65
Vldlr	D19Mit29	2	50
D19Ucla2	D19Mit29	2	50
D19Ucla3	D19Mit29	2	50
D19Mit29	D19Mit31	4	49
D19Mit31	D19Ucla4	5	57
D19Ucla4	D19Mit14	1	62
D19Mit14	D19Mit12	6	49
D19Mit12	D19Ucla5	4	51
D19Ucla5	Pdcd4	3	60
Pdcd4	D19Mit4	5	55
D19Mit4	D19Mit1	1	61
D19Mit1	Pnlip	2	62
D19Mit1	Pnliprp1	2	62
Pnlip	Pnliprp1	0	66
Pnlip	D19Mit6	1	61
Pnliprp1	D19Mit6	1	61

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Fth1	Vldlr	1	67	1.493	1.481
Fth1	D19Ucla2	1	67	1.493	1.481
Fth1	D19Ucla3	1	67	1.493	1.481
Vldlr	D19Ucla2	0	65	0.000	0.000
Vldlr	D19Ucla3	0	65	0.000	0.000
D19Ucla2	D19Ucla3	0	65	0.000	0.000
Vldlr	D19Mit29	2	52	3.846	2.667
D19Ucla2	D19Mit29	2	52	3.846	2.667
D19Ucla3	D19Mit29	2	52	3.846	2.667
D19Mit29	D19Mit31	4	53	7.547	3.628
D19Mit31	D19Ucla4	5	62	8.065	3.458
D19Ucla4	D19Mit14	1	63	1.587	1.575
D19Mit14	D19Mit12	6	55	10.909	4.204
D19Mit12	D19Ucla5	4	55	7.273	3.502
D19Ucla5	Pdcd4	3	63	4.762	2.683
Pdcd4	D19Mit4	5	60	8.333	3.568
D19Mit4	D19Mit1	1	62	1.613	1.600
D19Mit1	Pnlip	2	64	3.125	2.175
D19Mit1	Pnliprp1	2	64	3.125	2.175
Pnlip	Pnliprp1	0	66	0.000	0.000
Pnlip	D19Mit6	1	62	1.613	1.600
Pnliprp1	D19Mit6	1	62	1.613	1.600