Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  11
• Reference
  J:36967 Sornson MW, et al., Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism. Nature. 1996 Nov 28;384(6607):327-33
• ID
  MGI:48265

Genes

Gene	Allele	Assay Type
D11Mit22		PCR amplified length variant
Pad1		reported elsewhere
D11Mit139		PCR amplified length variant
D11Mit153		PCR amplified length variant
Prop1	Prop1^df	visible phenotype
D11Mit87		PCR amplified length variant
D11Mit24		PCR amplified length variant
Il4		reported elsewhere
Il5		reported elsewhere
D11Mit140		PCR amplified length variant
Il3		reported elsewhere
Csf2		reported elsewhere

Notes

• Experiment
  Genetic mapping using a CAST/Ei x C57BL/6J intercross and a Mus spretus x C57BL/6J backcross provided the following order of loci on mouse Chromosome 11: D11Mit22 - Pad1 - D11Mit139 - D11Mit153 - Prop1 - D11Mit87 - D11Mit24 - Il4 - Il5 - D11Mit140 - Il3 - Csfgm. These data were used to identify the genomic region coding for the df phenotype, and to positionally clone Prop1.