Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  12
• Reference
  J:163308 Speca DJ, et al., Conserved role of unc-79 in ethanol responses in lightweight mutant mice. PLoS Genet. 2010;6(8)
• ID
  MGI:4830366

Genes

Gene	Description
Unc79	Unc79
D12Mit158
D12Mit263
D12Mit180
D12Mit195

Notes

• Experiment
  DBA/2J (D2) male mice were administered ENU. The ENU mice were bred to nonmutagenized D2 female mice to produce G1 mutagenized male mice and then backcrossed to C57BL/6J females. High-scoring mice for locomotor Activity were then backcrossed repeatedlyto B6 females for heritability testing and QTL mapping.
  
  QTL mapping showed a QTL for locomotor activity (Lwt) mapping to mouse Chromosome 12 between D12Mit158 and D12Mit263. Lwt was subsequently determined to be an allele of the Unc79 locus
  
  Further genetic mapping showed the Lwt mutant phenotype to map between D12Mit180 and D12Mit195 or to a physical location between (NCBI build v37) 104.18 Mb and 104.42 Mb wherein Unc79 resides.