Mapping Data

Experiment

• Experiment
  TEXT-Physical Mapping
• Chromosome
  5
• Reference
  J:40181 George S, et al., Physical mapping of the murine casein locus reveals the gene order as alpha-beta-gamma-epsilon-kappa. DNA Cell Biol. 1997 Apr;16(4):477-84
• ID
  MGI:48492

Genes

Gene	Assay Type	Description
Csn1s1	restriction analysis	490 H23
Csn2	restriction analysis	490 H23
Csn1s2a	restriction analysis	490 H23, 555 N16
Csn1s2b	restriction analysis	555 N16
Csn3	restriction analysis	555 N16

Notes

• Experiment
  Authors physically mapped members of the casein gene family to mouse Chromosome 5 using restriction analysis of two overlapping BAC clones. Csn1s1 and Csn2 were mapped in close proximity to each other with an intergenic region of ~8kb, and Csn1s2b was located~20kb away from Csn1s2a. The distance between Csn2 and Csn1s2a was determined to be ~55kb and was ~40kb between Csn1s2b and Csn3. This data shows that the murine casein gene family is contained within a 250kb region on mouse Chromosome 5 in the following gene order: Csn1s1 - Csn2 - Csn1s2a - Csn1s2b - Csn3.